C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) C07K 7/08 (2006.01)
Patent
CA 2250361
The present invention provides peptides of human myelin oligodendrocyte glycopeptide (MOG), an autoantigen related to demyelinating autoimmune diseases. The present invention also provides compositions including MOG peptides or mixtures of MOG peptides and myelin basic peptide (MBP) peptides. Also provided are therapeutic compositions useful for diagnosing and treating autoimmune diseases, and methods of treating multiple sclerosis using such therapeutic compositions.
La présente invention concerne des peptides de la glycoprotéine d'oligodendrocyte de myéline humaine (MOG), auto-antigène lié aux maladies auto-immunes démyélinissantes. La présente invention concerne également certaines compositions incluant des peptides MOG ou des mélanges de peptides MOG et de peptides du peptide MBP. Enfin, la présente invention concerne aussi certaines compositions thérapeutiques servant au diagnostic et au traitement de certaines maladies auto-immunes ainsi que des méthodes de traitement de la sclérose en plaques au moyen desdites compositions thérapeutiques.
Devaux Brigitte
Garman Richard D.
Rothbard Jonathan
Smilek Dawn
Wallner Barbara
Devaux Brigitte
Garman Richard D.
Gowling Lafleur Henderson Llp
Immulogic Pharmaceutical Corporation
Rothbard Jonathan
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