Mylks as modifiers of branching morphogenesis and methods of...

Details Mylks as modifiers of branching morphogenesis and methods of... Mylks as modifiers of branching morphogenesis and methods of...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2527908

Human MYLK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MYLK are provided.

L'invention concerne des gènes MYLK humains identifiés en tant que modulateurs de la morphogenèse ramifiée, consistant donc en des cibles thérapeutiques contre des troubles associés à une fonction défectueuse de la morphogenèse ramifiée. Les procédés d'identification de modulateurs de morphogenèse ramifiée consistent à cribler des agents qui modulent l'activité de MYLK.

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