Myostatin antagonists

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/475 (2006.01) A61K 38/18 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 19/10 (2006.01) A61P 21/06 (2006.01) C07K 14/435 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2693378

An isolated recombinant polypeptide having myostatin antagonist activity, comprising a C-terminally truncated mature myostatin peptide, wherein the C-terminal truncation is at a position at or between amino acids 281 and 329, or a fragment, variant or derivative thereof.

Polypeptide de recombinaison isolé à activité antagoniste vis-à-vis de la myostatine, comprenant un peptide de myostatine mature tronqué en terminaison C, laquelle est en position sur ou entre acides aminés 281 et 329, y compris un fragment, variant ou dérivé correspondant.

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