Myotonin receptors and screening methods

Details Myotonin receptors and screening methods Myotonin receptors and screening methods

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 16/28 (2006.01) G01N 33/554 (2006.01) G01N 33/567 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2105167

2105167 9314408 PCTABS00024 Purified myotonin receptors, nucleic acid encoding such receptors, and methods for identifying or screening or characterizing or assaying or isolating known or candidate compounds useful for treatment of a hypoglycemic condition, or a disease characterized by insulin resistance, including binding assays utilizing preparations containing specific myotonin receptors are described. Membranes from leiomyosarcoma cells that contain myotonin receptors are particularly useful for the methods of this invention, and as a source of myotonin receptor protein.

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