N-(1-((1,3-dihydro-1,3-dioxo-2h-benz(de)...

C - Chemistry – Metallurgy – 07 – D

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260/277.3

C07D 221/14 (2006.01) C07D 401/06 (2006.01)

Patent

CA 1070311

ABSTRACT Compounds of the following formula and their acid addition salts Image wherein R1 and R2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, amino and trifluoromethyl; A is a straight or branched chain alkylene of 1 to 8 carbons; R3 is phenyl or substituted phenyl; and R is lower alkyl or cycloalkyl of 3 to 7 carbons are disclosed. These compounds exhibit antidepressant activity. In addition these compounds are useful as antiinflammatory agents.

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