N-[[1-[4-(4-fluorophenoxy)butyl]...

Details N-[[1-[4-(4-fluorophenoxy)butyl]... N-[[1-[4-(4-fluorophenoxy)butyl]...

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2163018

2-[[1-[4-(4-fluorophenoxy)butyl]-4- piperidinyl]methylamino]-benzothiazololes of formula (I), wherein R1 or R2 is hydroxy, the other variable always being hydrogen, and the pharmaceutically acceptable acid addition salts thereof. Novel compounds, pharmaceutical compositions, as well as their use as a class III antiarrhythmicum is disclosed.

2-[[1-[4-(4-fluorophénoxy)butyl]-4-pipéridinyl]méthylamino]-benzothiazololes de formule (I), dans laquelle R<1> ou R<2> représente hydroxy, l'autre variable représentant toujours hydrogène, et des sels d'addition d'acide pharmaceutiquement acceptables de ces derniers. Des nouveaux composés, des compositions pharmaceutiques ainsi que leur utilisation en tant qu'antiarythmicum de classe II sont également décrits.

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