N-(1-substituted-3-pyrrolidinyl)-1-naphthalene and...

Details N-(1-substituted-3-pyrrolidinyl)-1-naphthalene and... N-(1-substituted-3-pyrrolidinyl)-1-naphthalene and...

C - Chemistry, Metallurgy

07

D

260/325.2, 260/2

C07D 401/12 (2006.01) C07D 207/14 (2006.01) C07D 215/50 (2006.01)

Patent

CA 1071636

ABSTRACT OF THE DISCLOSURE Novel N-(1-substituted-3-pyrrolidinyl)-1-naphthalene- and 4-gyinolinecarboxamides of the formula: Image wherein R is lower cycloalkyl, R1 is hydrogen, lower alkyl or aryl, R2 is hydrogen, lower-alkyl, halogen, lower-alkoxy, amino or nitro, R3 is hydrogen, lower-alkyl, halogen, lower alkoxy, amino or nitro, Y is -CH- or nitrogen and pharma- ceutically acceptable acid addition salts thereof having anti-emetic properties are disclosed.

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