C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/47 (2006.01) A61K 31/513 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2309546
This invention comprises the compound (1) and the pharmaceutically acceptable salts thereof. Compound (1) is an interleukin-1.beta. converting enzyme inhibitor and is useful for treating inflammatory diseases such as arthritis and inflammatory bowel disease, septic shock, reperfusion injury, shigellosis, and neuroinflammatory disorders such as stroke, multiple sclerosis, and Alzheimer's disease.
L'invention porte sur le composé de formule (1) et sur ses sels pharmacocompatibles. Ledit composé, inhibiteur de l'enzyme de conversion de l'interleukine-1.beta., sert au traitement de troubles inflammatoires telles que l'arthrite et les inflammations des intestins, le choc septique, les lésions de reperfusion, la shigellose, et de troubles neuroinflammatoires tels que les attaques, la sclérose en plaques et la maladie d'Alzheimer.
Schielke Gerald Paul
Shahripour Aurash
Basf Aktiengesellschaft
Macrae & Co.
Warner-Lambert Company
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