C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
260/230.58
C07H 5/06 (2006.01) A61K 39/39 (2006.01) C07H 13/04 (2006.01) C07H 13/12 (2006.01)
Patent
CA 1289952
Abstract Compounds of the formula Image in which R1 denotes hydrogen or a saturated or singly or multiply unsaturated alkyl radical having up to 50 carbon atoms, X represents -CH2-, -O- or -NH-, R2 denotes hydrogen or a saturated or singly or multiply unsaturated alkyl radical having up to 50 carbon atoms, R3, R4 and R5, independently of one another, denotes hydrogen or acyl-CO-R6, R6 being an alkyl radical having up to 10 carbon atoms, R7 denotes hydrogen, C1-C7-alkyl-, hydroxy- methyl, 1-hydroxyethyl, mercaptomethyl, 2- (methylthio)-ethyl, 3-aminopropyl, 3-ureidoprop- yl, 3-guanidyl-propyl, 4-aminobutyl, carboxy- methyl, carbamylmethyl, 2-carboxyethyl, 2- carbamoylethyl, benzyl, 4-hydroxybenzyl, 3- indolylmethyl or 4-imidazolylmethyl, and R8 represents hydrogen or methyl, and R9 represents hydrogenl acetyl, benzoyl, tri- chloroacetyl, trifluoroacetyl, methoxycarbonyl, t-butyloxycarbonyl or benzyloxycarbonyl and Le A 23 620 Abstract (Continued) R7 and R8 together can denote -CH2-CH2-CH2, and pharmaceutically acceptable salts thereof stimulate the immune system and can be used in conjunction with antibiotics and vaccines. New intermediates are also shown. Le A 23 620
511894
Brunner Helmut
Hayauchi Yutaka
Klimetzek Volker
Kroll Hein-Peter
Lockhoff Oswald
Bayer Healthcare Ag
Fetherstonhaugh & Co.
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