N-(2-aryl-propionyl)-sulfonamides and pharmaceutical...

Details N-(2-aryl-propionyl)-sulfonamides and pharmaceutical... N-(2-aryl-propionyl)-sulfonamides and pharmaceutical...

C - Chemistry, Metallurgy

07

C

C07C 311/51 (2006.01) A61K 31/18 (2006.01) C07C 303/36 (2006.01)

Patent

CA 2347752

The compounds of formula (1), wherein R and R2 are as defined in the disclosure, are useful in the prevention and treatment of tissue damage due to exacerbated recruitment of polymorphonuclear neutrophils (PMN leukocytes) at the inflammatory sites.

On décrit des composés de formule (1) dans laquelle R et R2 sont tels que définis dans le descriptif. Ces composés sont utiles dans la prophylaxie et le traitement des détériorations tissulaires dues au recrutement accru des neutrophiles polymorphonucléaires (leucocytes PMN) au niveau des sites inflammatoires.

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