N-{ '(2s) -4- (3, 4-difluorobenzyl) morpholin-2yl]methyl}...

Details N-{ '(2s) -4- (3, 4-difluorobenzyl) morpholin-2yl]methyl}... N-{ '(2s) -4- (3, 4-difluorobenzyl) morpholin-2yl]methyl}...

C - Chemistry, Metallurgy

07

D

C07D 265/30 (2006.01) A61K 31/5375 (2006.01)

Patent

CA 2479910

Compound of formula (I): HsC H H '(0) IIZZ V which is; 3-(f [({[(2S)-4-(3,4- dichlorobenzyl)morpholin-2-yl]methyl}amino)carbonyl]- amino}methyl)=Nethlylbenzamide; and salts and solvates thereof, a process for its preparation intermediates, pharmaceutical formulations containing it and its use in therapy, as CCR3=antagonist for the treatment of inflammatory conditions.

L'invention concerne un composé de formule générale (I) qui est un 3-({[({[ (2S)-4-(3,4-dichlorobenzyle)morpholine-2-yle]méthyle}amino)carbonyle]-amino}méthyle)-N-éthylbenzamide; ainsi que des sels et des solvates de celui-ci, un procédé pour ses intermédiaires de préparation, des formulations pharmaceutiques le contenant et son utilisation à des fins thérapeutiques, en tant qu'antagoniste du récepteur CCR3 pour le traitement d'états inflammatoires.

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