C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/78 (2006.01) A61K 31/165 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 31/55 (2006.01) C07C 233/88 (2006.01) C07D 209/44 (2006.01) C07D 217/04 (2006.01) C07D 217/14 (2006.01) C07D 223/16 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2141729
Compounds of the formula: Image (I) in which R1 represents a hydrogen or halogen atom or a methyl or C1-C4 alkoxy group, R'1 represents a hydrogen or halogen atom, R"1 represents a hydrogen atom or a methoxy group, R3 represents a C1-C3 alkyl group, R4 represents a 2,3-dihydro-1H-inden-2-yl, 2,3-dihydro-1H- inden-1-yl or 1,2,3,4-tetrahydronaphthalen-1-yl group, or R3 and R4 together form, with the adjacent nitrogen atom, a 1,2,3,4-tetrahydroisoquinol-2-yl, 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinol-2-yl, 5,8- dimethoxy-1,2,3,4-tetrahydroisoquinol-2-yl, 1,2,3,4- tetrahydro-9H-pyrido[3,4-b]indol-2-yl, 1,2,3,4- tetrahydro-9H-pyrido[4,3-b]indol-3-yl, 4,5,6,7- tetrahydrothieno[2,3-c]pyrid-6-yl, 2,3-dihydro-1H- isoindol-2-yl or 2,3,4,5-tetra-hydro-1H-3-benzazepin- 3-yl, group are useful in the treatment of cerebral disorders.
Bartsch Regine
Frost Jonathan
George Pascal
Muller Jean Claude
Pasau Patrick
Kirby Eades Gale Baker
Sanofi-Synthelabo
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