N-(3-ethynylphenyl-6,7-bis(2-methoxyethoxy)-4-quinazolinamin...

Details N-(3-ethynylphenyl-6,7-bis(2-methoxyethoxy)-4-quinazolinamin... N-(3-ethynylphenyl-6,7-bis(2-methoxyethoxy)-4-quinazolinamin...

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2330447

The present invention relates to the anhydrous and hydrate forms of N-(3- ethynylphenyl)-6,7-bis (2-methoxyethoxy)4-quinazolinamine mesylate. The invention also relates to pharmaceutical compositions containing N- (3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate and to methods of treating hyperproliferative disorders, such as cancer, by administering N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4- quinazolinamine mesylate.

La présente invention concerne les formes anhydrides et hydratées de N- (3-éthynylphényle)-6-,7- bis(2)méthoxyéthoxy)-4-quinazolinamine mésylate. L'invention concerne également des compositions pharmaceutiques contenant le N- (3-éthynylphényle)-6,7- bis(2)-méthoxyéthoxy)-4- quinazolamine mésylate ainsi que des méthodes de traitement de troubles hyperprolifératifs, tels que le cancer, par administration de N- (3-éthynylphényle)-6,7- bis(2)-méthoxyéthoxy)- 4-quinazoline mésylate.

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