C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/60 (2006.01) A61K 31/395 (2006.01) A61K 31/695 (2006.01) C07D 211/56 (2006.01) C07D 401/06 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/00 (2006.01) C07D 413/06 (2006.01) C07D 417/14 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2157792
This invention relates to .beta.-alanine derivatives represented by formula (I), wherein each symbol is as defined in the specification and pharmaceutically acceptable salt thereof which is glycoprotein IIb/IIIa antagonist, inhibitor of blood platelets aggregation and inhibitor of the binding of fibrinogen to blood platelets, to processes for the preparation thereof, to a pharmaceutical composition comprising the same and to a method for the prevention and/or treatment of diseases indicated in the specification to a human being or an animal.
L'invention se rapporte à des dérivés de beta -alanine représentés par la formule (I), dans laquelle chaque symbole a la même notation que dans la description, et à un sel de ces dérivés acceptable en pharmacologie, qui est un antagoniste de la glycoprotéine IIb/IIIa, un inhibiteur de l'agrégation des plaquettes sanguines et un inhibiteur de la liaison du fibrinogène aux plaquettes sanguines. L'invention se rapporte également à des procédés de préparation de ce composé, à une composition pharmaceutique le contenant et à un procédé de prévention et/ou de traitement de maladies énumérées dans la description, chez l'homme ou l'animal.
Kato Masayuki
Ohkubo Mitsuru
Sakai Hiroyoshi
Takahashi Fumie
Yamanaka Toshio
Fujisawa Pharmaceutical Co. Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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