N-(4-carbamimido-phenyl)-phenylglycinamid derivatives

Details N-(4-carbamimido-phenyl)-phenylglycinamid derivatives N-(4-carbamimido-phenyl)-phenylglycinamid derivatives

C - Chemistry, Metallurgy

07

C

C07C 257/18 (2006.01) A61K 31/16 (2006.01) A61K 31/195 (2006.01) A61K 31/27 (2006.01) A61K 31/33 (2006.01) C07C 255/58 (2006.01) C07C 255/59 (2006.01) C07C 259/18 (2006.01) C07C 271/64 (2006.01) C07C 311/08 (2006.01) C07C 311/21 (2006.01) C07C 311/46 (2006.01) C07D 207/16 (2006.01) C07D 209/08 (2006.01) C07D 209/20 (2006.01) C07D 211/60 (2006.01) C07D 213/30 (2006.01) C07D 213/40 (2006.01) C07D 213/58 (2006.01) C07D 213/69 (2006.01) C07D 215/14 (2006.01) C07D 217/02 (2006.01) C07D 217/26 (2006.01) C07D 233/

Patent

CA 2255180

The novel N-(4-carbamimidophenylamino)phenyl- glycineamide derivatives of the formula (see fig. I) in which E, G1, G2, Q, R and X1 to X4 are each as defined in the description, and hydrates or solvates and physiologically acceptable salts thereof can be used as inhibitors of the formation of the coagulation factors Xa, IXa and thrombin induced by the factor VIIa and by the tissue factor, specifically as medicaments for the treatment and/or prevention of thromboses, apoplexy, cardiac infarction, inflammation and arteriosclerosis or as antitumour agents.

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