N-¬4-o-hydroxyphenyl-1,3-dioxan-5-yl-hexenoyl|sulphonamides

Details N-¬4-o-hydroxyphenyl-1,3-dioxan-5-yl-hexenoyl|sulphonamides N-¬4-o-hydroxyphenyl-1,3-dioxan-5-yl-hexenoyl|sulphonamides

C - Chemistry, Metallurgy

07

D

167/123, 167/244

C07D 319/06 (2006.01) A61K 31/335 (2006.01) C07C 45/41 (2006.01)

Patent

CA 1284331

A B S T R A C T AMIDE DERIVATIVES The invention concerns novel N-[4(Z)-6-(4-0- hydroxyphenyl-1,3-dioxan-cls-5-yl)hexenoyl]sulphonamide derivatives of formula I of value as therapeutic agents. R1 is typically an alkoxyalkyl or phenoxyalkyl radical as defined hereinafter and R2 is alkyl, benzyl or phenyl. The invention also discloses salts of the formula I compounds as well as pharmaceutical compositions containing the compounds and processes for the production of the compounds.

522420

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