N-acyl acidic amino acid diamide derivative, a salt thereof,...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/54 (2006.01) A61K 31/34 (2006.01) C07D 211/58 (2006.01) C07D 213/56 (2006.01) C07D 213/81 (2006.01) C07D 241/08 (2006.01) C07D 277/56 (2006.01) C07D 295/15 (2006.01) C07D 295/185 (2006.01) C07D 295/20 (2006.01) C07D 295/215 (2006.01) C07D 307/46 (2006.01) C07D 307/68 (2006.01) C07D 307/79 (2006.01) C07D 307/81 (2006.01) C07D 309/38 (2006.01) C07D 311/12 (2006.01) C07D 311/66 (2006.01) C07D 333/24 (2006.01) C07D 333/38 (2006.01) C07D 333/60 (2006.01) C07D 407/12 (2006.01)

Patent

CA 1265801

ABSTRACT OF THE DISCLOSURE This invention relates to a novel N-acyl acidic amino acid diamide derivative represented by the general formula or a salt thereof: Image whexein each of R1, R2, R3 and R4, which may be the same or different, represents a hydrogen atom or a substituted or unsubstituted alkyl, cycloalkyl, alkenyl or aralkyl group, or R1 and R2 and/or R3 and R4, when taken together with the respective adjacent nitrogen atoms, form a substituted or unsubstituted heterocyclic group; R5 represents a substituted or unsubstituted cycloalkyl, acyl or heterocyclic group; A represents a bond or a substituted or unsubstituted alkylene, alkenylene or alkadienylene group, and n is 1, 2 or 3. Said compound has an anti-ulcer activity which is effective to human beings and animals. This disclosure relates to such a compound, to a process for the production thereof and to an anti-ulcer agent containing the same.

468866

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