N-acyl and n-aroyl aralkyl amides

Details N-acyl and n-aroyl aralkyl amides N-acyl and n-aroyl aralkyl amides

C - Chemistry, Metallurgy

07

D

C07D 295/155 (2006.01) A61K 31/165 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07C 233/78 (2006.01) C07C 317/32 (2006.01) C07C 323/42 (2006.01) C07D 207/09 (2006.01) C07D 207/14 (2006.01) C07D 209/42 (2006.01) C07D 211/34 (2006.01) C07D 241/04 (2006.01) C07D 241/42 (2006.01) C07D 263/34 (2006.01) C07D 295/073 (2006.01) C07D 295/13 (2006.01) C07D 295/135 (2006.01) C07D 333/38 (2006.01) C07D 453/02 (2006.01) C07D

Patent

CA 2269049

Disclosed are compounds of the formula: (see formula I) (wherein R1 is typically a cyclic amino such as piperazinyl; R2 is hydrogen or alkyl optionally substituted by phenyl, naphthyl or heteroaryl; X, R3, R4 and R5 are each hydrogen or substituent; and m is 0-4) useful in treating or preventing migraine, depression and other disorders for which a 5-HT1 agonist or antagonist is indicated.

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