N-acyl-n-norsalutaridines and process for making them

Details N-acyl-n-norsalutaridines and process for making them N-acyl-n-norsalutaridines and process for making them

C - Chemistry, Metallurgy

07

D

260/237.69

C07D 221/28 (2006.01)

Patent

CA 1064923

ABSTRACT OF THE DISCLOSURE N-acyl-M-norsalutaridines can be made by oxidative coup- ling of N-acyl-N-norreticulines using thallium tristrifluoro- acetate or a coordinating agent and an oxidizing agent. The N-acyl-N-norsalutaridines can be converted to thebaine, N-northebaine, and N-substituted-N-northebaines, which can be converted to opium alkaloids and related compounds.

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