N-acyl peptide compound, process for the preparation thereof...

Details N-acyl peptide compound, process for the preparation thereof... N-acyl peptide compound, process for the preparation thereof...

C - Chemistry, Metallurgy

12

P

530/5, 195/128.7

C12P 21/02 (2006.01) C07K 5/062 (2006.01) C12P 13/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1170599

ABSTRACT OF THE DISCLOSURE N-acyl peptides of the formula: Image wherein R1 and R2 are each alkyl or alkenyl R3 is hydrogen, lower alkyl, hydroxy(lower)alkyl, heterocyclic(lower)alkyl or ar(lower)alkyl, wherein the aryl moiety may have hydroxy or protectod hydroxy, R4 is carboxy, esterified carboxy. carboxy(lower)alkyl or esterified carboxy(lower)alkyl, X is bond or lower alkylene; Y is lower alkylene or lower alkylldene and n is an integer of 0 or 1; and pharmaceuti- cally acceptable salts, have anticomplemantary activity and fibrinolytic activity and may be used in the treatment of immune-complex diseases or autoimmune diseases.

392320

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