N - (acyldipeptidyl) - aminoglycols

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

167/103.05, 530/

C07K 5/06 (2006.01) C07K 5/02 (2006.01) C07K 5/065 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1261546

ABSTRACT 1. A compound of the formula: Image wherein R1 is alkoxy containing one to six carbon atoms or lower alkyl containing one to six carbon atoms; R2 is benzyl or napthylmethyl, R3 is lower alkyl containing one to six carbon atoms or imidazolemethyl; R4 is benzyl, R5 is hydrogen or lower alkyl and n is 0 or 1. These compounds are useful as renin inhibitors.

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