N-acylpyrrolidine derivative and synthesis and use thereof

Details N-acylpyrrolidine derivative and synthesis and use thereof N-acylpyrrolidine derivative and synthesis and use thereof

C - Chemistry, Metallurgy

07

D

167/233, 260/325

C07D 207/04 (2006.01) A61K 31/40 (2006.01) C07D 207/08 (2006.01) C07D 207/16 (2006.01)

Patent

CA 1267149

ABSTRACT An N-acylpyrrolidine derivative of the formula (I): Image (I) wherein R1 is hydrogen atom, a lower alkyl group or phenyl group, R3 is a lower alkyloxycarbonyl group, hydroxymethyl group or formyl group, when R1 is hydrogen atom, R2 is phenyloxy, phenylcarbonyl, halophenyloxy, C1-4 alkoxyphenyloxy, halophenyl, C1-4 alkoxyphenyl, and when R1 is a lower alkyl group or phenyl group, R2 is phenyl, halophenyl, C1-4 alkoxy- phenyl, a lower alkyl group, an aralkyl group of 7 to carbon atoms or hydroxy group; or R1 and R2 together form a benzylidene group which is unsub- stituted or substituted on its aromatic moiety by a halogen atom or C1-4 alkoxy, and n is an integer of 0 to 5, exhibit inhibitory activity against prolyl endopeptidase, and may be used as a prolyl endopep- tidase inhibitor and an anti-amnesic agent.

506768

Affiliated with

Also associated with

Rating

N-acylpyrrolidine derivative and synthesis and use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-acylpyrrolidine derivative and synthesis and use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-acylpyrrolidine derivative and synthesis and use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1257747