N-adamantane-substituted tetrapeptide amides

Details N-adamantane-substituted tetrapeptide amides N-adamantane-substituted tetrapeptide amides

C - Chemistry, Metallurgy

07

K

530/7, 530/7.12

C07K 5/02 (2006.01) C07K 5/06 (2006.01) C07K 5/103 (2006.01) C07K 5/107 (2006.01) C07K 7/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1151642

2174 U.S. MAZUR N-ADAMANTANE-SUBSTITUTED TETRAPEPTIDE AMIDES ABSTRACT OF THE DISCLOSURE N-Adamantane-substituted tetrapeptide amides and the pharmacologically acceptable salts thereof are disclosed herein. These compounds are analogs of enkephalin wherein the methionine or leucine of position 5 has been substituted by an adamantyl amide and the glycine of position 2 has been substituted by various amino acid residues. Optionally the tyrosine of position 1 and the phenylalanine of position 4 may be substituted by various amino acid residues. These compounds exhibit agonist activity at opiate receptor sites and are useful as analgesics.

365903

Affiliated with

Also associated with

Rating

N-adamantane-substituted tetrapeptide amides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-adamantane-substituted tetrapeptide amides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-adamantane-substituted tetrapeptide amides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-286049