N-alkoxyalkyl-n,n-dialkylamine derivatives or salts thereof,...

Details N-alkoxyalkyl-n,n-dialkylamine derivatives or salts thereof,... N-alkoxyalkyl-n,n-dialkylamine derivatives or salts thereof,...

C - Chemistry, Metallurgy

07

C

C07C 217/10 (2006.01) A61K 31/135 (2006.01) A61K 31/343 (2006.01) A61K 31/352 (2006.01) A61K 31/357 (2006.01) A61K 31/36 (2006.01) A61K 31/381 (2006.01) A61K 31/4184 (2006.01) A61K 31/428 (2006.01) A61K 31/4436 (2006.01) A61K 31/47 (2006.01) A61K 31/498 (2006.01) A61P 11/16 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) C07C 233/69 (2006.01) C07D 215/14 (2006.01) C07D 235/06 (2006.01) C07D 241/42 (2006.01) C07D 277/64 (2006.01) C07D 307/79 (2006.01) C07D 311/04 (2006.01) C07D 317/5

Patent

CA 2374659

N-Alkoxyalkyl-N,N-dialkylamine derivatives of general formula [1] or salts thereof, which exhibit antihypoxic, nerve protecting and nerve regeneration promoting effects and are useful as remedies for nerve degeneration diseases, wherein R1 and R2 are each hydrogen, halogeno, or the like; R3 and R4 are each optionally substituted alkyl, cycloalkyl, or aralkyl; R5, R6, R7 and R8 are each hydrogen or alkyl; D is a five- or six-membered heterocycle or a hydrocarbon ring; m is 1 to 5; and n is 1 to 6.

L'invention concerne des dérivés de N-alkoxyalkyl, N-dialkylamine représentés par la formule générale [1] ci-dessous, ou leurs sels, qui ont des effets antihypoxiques, de protection nerveuse ou qui favorisent la régénération nerveuse, et qui servent de remèdes contre les maladies à dégénérescence nerveuse. Dans cette formule, R?1¿ et R?2¿ sont, chacun, hydrogène, halogéno ou analogue; R?3¿ et R?4¿ sont, chacun, alkyle, cycloalkyle ou aralkyle facultativement substitué; R?5¿, R?6¿, R?7¿ et R?8¿ sont, chacun, hydrogène ou alkyle; D est un hétérocycle à cinq ou six éléments ou un noyau d'hydrocarbure ; m vaut de 1 à 5 et n de 1 à 6.

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