N-alkyl-2-substituted atp analogues

C - Chemistry – Metallurgy – 07 – H

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C07H 19/20 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2155673

There are disclosed compounds of formula (I) wherein R1 and R2 independently represent hydrogen or halogen, R3 and R4 independently represent phenyl, or alkyl C1-6 optionally substituted by one or more substituents selected from OR5, alkylthio C1-6, NR6R7, phenyl, COOR8 and halogen, R5, R6, R7 and R8 independently represent hydrogen or alkyl C1-6, an X represents an acidic moiety, and pharmaceutically acceptable salts thereof. Processes for their production and pharmaceutical compositions and methods of treatment involving their use are also described.

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