N-alkyl peptide chelate formers, their metal complexes with...

Details N-alkyl peptide chelate formers, their metal complexes with... N-alkyl peptide chelate formers, their metal complexes with...

C - Chemistry, Metallurgy

07

K

C07K 5/083 (2006.01) A61K 51/04 (2006.01) A61K 51/08 (2006.01) C07C 323/52 (2006.01) C07C 327/20 (2006.01) C07D 457/06 (2006.01) C07D 457/12 (2006.01) C07F 5/00 (2006.01) C07F 13/00 (2006.01) C07J 41/00 (2006.01) C07J 51/00 (2006.01) C07K 2/00 (2006.01) C07K 5/06 (2006.01) C07K 5/062 (2006.01) C07K 5/08 (2006.01) C07K 14/575 (2006.01)

Patent

CA 2173844

The invention relates to N-alkyl peptide chelate formers, their metal complexes with radionuclides, processes for their production and radio-pharmaceutical compositions containing these compounds. The invention also relates to radio-pharmaceuticals containing these chelates in metal-complexed form, diagnostic kits in which the chelate may be present in non-complexed form and is complexed by the addition of either technetium or rhenium ions, and the use of such preparations for diagnostic and therapeutic purposes.

L'invention concerne des chélateurs N-alkylpeptidiques, leurs complexes métalliques avec des radionucléides, des procédés pour leur préparation et des compositions radiopharmaceutiques contenant ces composés. L'invention concerne également des produits radiopharmaceutiques contenant ces chélates sous une forme complexée avec des métaux, des trousses de diagnostic dans lesquelles le chélate peut se présenter sous une forme non complexée et être complexé par addition d'ions technétium ou rhénium, et elle concerne également l'utilisation de ces préparations à des fins diagnostiques et thérapeutiques.

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