N-alkylated quaternary nitrogen-containing heterocycles

Details N-alkylated quaternary nitrogen-containing heterocycles N-alkylated quaternary nitrogen-containing heterocycles

C - Chemistry, Metallurgy

07

D

167/163, 167/179

C07D 235/08 (2006.01) A61K 9/107 (2006.01) A61K 47/18 (2006.01) C07D 213/20 (2006.01) C07D 213/30 (2006.01) C07D 213/63 (2006.01) C07D 213/65 (2006.01) C07D 213/68 (2006.01) C07D 213/69 (2006.01) C07D 213/73 (2006.01) C07D 213/80 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 233/54 (2006.01) C07D 235/06 (2006.01) C07D 239/26 (2006.01) C07D 239/30 (2006.01) C07D 239/36 (2006.01) C07D 239/46 (2006.01) C07D 239/47 (2006.01) C07D 239/54 (2006.01) C07D 239/553 (2006.01) C07D 241/24 (2006.01) C07D 27

Patent

CA 1332938

The synthesis of 7-n-alkyl-imidazolium[4,5-d]-pyrimidines, 6- substituted-3n-alkyl-benzimidazolium- and 3n-alkyl-5,6-substi- tuted-benzthiazolium salts are described. These N+-surfactants having a substituted heterocycle as a head group have distinguished small critical micelle concentrations (CMC) in the range of 10-5-10-7 Mol/Liter. The size and shape of these micelles in watery solutions are determined by the nature of the anion. The N-surfactants can be used as pharmaceuticals as well as reporter groups in fluorescence studies including immunological assays.

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