N-alkylated quaternary nitrogen-containing heterocycles

Details N-alkylated quaternary nitrogen-containing heterocycles N-alkylated quaternary nitrogen-containing heterocycles

C - Chemistry, Metallurgy

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C07D 213/68 (2006.01) A61K 9/107 (2006.01) A61K 47/00 (2006.01) A61K 47/18 (2006.01) C07D 213/20 (2006.01) C07D 213/30 (2006.01) C07D 213/63 (2006.01) C07D 213/65 (2006.01) C07D 213/69 (2006.01) C07D 213/73 (2006.01) C07D 213/80 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 233/54 (2006.01) C07D 235/06 (2006.01) C07D 239/26 (2006.01) C07D 239/30 (2006.01) C07D 239/36 (2006.01) C07D 239/46 (2006.01) C07D 239/47 (2006.01) C07D 239/54 (2006.01) C07D 239/553 (2006.01) C07D 241/24 (2006.01) C07D 277

Patent

CA 1332940

The synthesis of 4-, 4-(1,1)- and 3,5- substituted N-alkyl-pyri- dinium salts as well as of 2-carboxamide substituted N(1,4)dia- zinium componunds are described. The N-surfactants obtained have a small critical micelle concentration (CMC) of 10-5 - 10-7 Mol/ Liter. These surfactants produce micells of different size and form depending on the nature of the anions. 4-(1,1)-substituted and 3,5-substituted N-alkyl-pyridinium components are capable of forming vesicles in equeous solutions of different forms and sizes. The N-surfactants synthesized can be used as pharma- ceuticals.

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