N-¬.alpha.-(4-r-1-piperazinyl)-alkyl|bicyclo...

Details N-¬.alpha.-(4-r-1-piperazinyl)-alkyl|bicyclo... N-¬.alpha.-(4-r-1-piperazinyl)-alkyl|bicyclo...

C - Chemistry, Metallurgy

07

D

260/263, 260/266

C07D 403/00 (2006.01) C07D 209/76 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 491/18 (2006.01)

Patent

CA 1184915

ABSTRACT The invention provides succinimide derivatives which can be represented by the following formula: Image (I) wherein X and Y are combined to form a group of the formula: Image (wherein A is an oxygen atom, a methylene group or an ethylene group and a full line accompanying a broken linc ( ? ) is a single bond or a double bond) and Z is a hydrogen atom or, X and Z are combined to form a group of the formula Image (wherein A and a full line are each as defined above) and Y is a hydrogen atom, R is a phenyl group, optionally substituted with halogen, C1-C4 alkyl, C1-C4 alkoxy or trifluoromethyl, a 2-pyridyl group or a 2-pyrimidinyl group and n is an integer of 3 or 4; and pharmaceutically acceptable acid addition salts thereof. These compounds have useful anti-anxiety effects in humans and animals.

417145

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