N-aryl azolone derivatives, the process for preparing the...

Details N-aryl azolone derivatives, the process for preparing the... N-aryl azolone derivatives, the process for preparing the...

C - Chemistry, Metallurgy

07

D

260/311.6

C07D 263/20 (2006.01) C07D 263/24 (2006.01)

Patent

CA 1171865

ABSTRACT OF THE DISCLOSURE Novel N-aryl 2-oxazolidinones of the formula: Image and their preparation. In the formula R designates: - the (3-acetyl) ethyloxy chain of formula: CH3CO-(CH2)2-0; - the (5-cyano) n-pentyl chain of formula: CN-(CH2)5; - the p-chlorophenyl or m-cyanophenyl nucleus; - the (2-cyclohexyl) ethynyl chain of formula: Image ; or - a group of structure: Image where R represents a halogen atom or the cyano group and the -A-B-chain has any one of the following means: -CH2CH2-, CO-CH2 -, -O-CH2 -, -C-C-, -CH2CH2-0. The compounds are useful in the treatment of endogenous and exogenous depression.

377905

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