C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/06 (2006.01) A61K 38/05 (2006.01) C07C 237/22 (2006.01) C07K 5/065 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2270876
Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
L'invention a trait à des composés inhibant la libération de peptide .beta.-amyloïde et ou sa synthèse et, de ce fait, se révélant utiles s'agissant de traiter la maladie d'Alzheimer. Elle a également trait à des compositions pharmaceutiques contenant un composé inhibant la libération de peptide .beta.-amyloïde et ou sa synthèse ainsi qu'à des méthodes de traitement de la maladie d'Alzheimer, tant au plan prophylactique que thérapeutique, ces méthodes faisant intervenir lesdites compositions pharmaceutiques.
Audia James E.
Folmer Beverly K.
John Varghese
Latimer Lee H.
Nissen Jeffrey S.
Elan Pharmaceuticals Inc.
Eli Lilly & Company
Gowling Lafleur Henderson Llp
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