N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical...

C - Chemistry – Metallurgy – 07 – C

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C07C 233/51 (2006.01) A61K 31/16 (2006.01) A61K 31/33 (2006.01) C07C 233/37 (2006.01) C07C 233/39 (2006.01) C07C 233/46 (2006.01) C07C 235/34 (2006.01) C07C 323/59 (2006.01) C07C 323/62 (2006.01) C07C 327/22 (2006.01) C07C 333/24 (2006.01) C07D 213/56 (2006.01) C07D 261/08 (2006.01) C07D 263/32 (2006.01) C07D 263/54 (2006.01) C07D 263/57 (2006.01) C07D 271/06 (2006.01) C07D 277/62 (2006.01) C07D 307/54 (2006.01) C07D 307/79 (2006.01) C07D 317/60 (2006.01) C07D 333/16 (2006.01) C07D 333/24 (2006.01) C07D 333

Patent

CA 2267065

Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

L'invention concerne des composés qui inhibent la libération du peptide de .beta.-amyloïde et/ou sa synthèse, et qui donc utiles dans le traitement de la maladie d'Alzheimer. Elle porte aussi sur des compositions pharmaceutiques comprenant un composé qui inhibe la libération du peptide de .beta.-amyloïde et/ou sa synthèse ainsi que sur des méthodes de traitement de la maladie d'Alzheimer de manière thérapeutique et prophylactique à l'aide desdites compositions.

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