N-aryl-n-¬4-(1-heterocyclicalkyl)piperidinyl| amides and...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/06 (2006.01) C07D 211/58 (2006.01) C07D 211/66 (2006.01) C07D 401/14 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07D 473/08 (2006.01) C07D 473/10 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2010425

ABSTRACT This invention pertains to novel substituted N/aryl-N-[4-(1- heterocyclicalkyl)piperidinyl]amides useful as analgesics, and methods of administering analgesia, which comprises the systemic administration to mammals of such compounds, and pharmaceutical compositions containing such compounds, wherein the novel compounds have the general formula: Image including optically active isomeric forms, and the pharmaceutically acceptable acid addition salts thereof, wherein R, R1, R2, R3 and R4 are defined in the disclosure.

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