N-aryl piperidine substituted biphenylcarboxamides as...

Details N-aryl piperidine substituted biphenylcarboxamides as... N-aryl piperidine substituted biphenylcarboxamides as...

C - Chemistry, Metallurgy

07

D

C07D 211/34 (2006.01) A61K 31/451 (2006.01) A61K 31/4545 (2006.01) A61K 31/506 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) C07D 211/62 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2494208

N-aryl piperidine substituted biphenylcarboxamides compounds of formula (I) methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes. The compounds act as inhibitors of apolipoprotein B.

Cette invention, qui a trait à des composés de biphénylcarboxamides à substitution N-aryl pipéridine correspondant à la formule (I), concerne également des procédés de préparation de ces composés, des compositions pharmaceutiques les contenant ainsi que l'usage qui est fait de ces composés comme médication destinée au traitement de l'hyperlipidémie, de l'obésité et du diabète de type II. Ces composés ont une action inhibitrice de l'alipoprotéine B.

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