C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/306, 260/326
C07D 207/48 (2006.01) C07D 307/68 (2006.01) C07D 333/28 (2006.01) C07D 333/38 (2006.01) C07D 403/12 (2006.01)
Patent
CA 1135705
ABSTRACT OF THE DISCLOSURE: Disclosed are compound of the formula 1 Image wherein R1 is alkyl of 2 to 5 carbon atom, alkyl, benzyl, furylmethyl wherein the furan ring may be substituted by bromine or thienylmethyl wherein the thiophene ring may he monosubstitu- ted by a methyl and R2 is hydrogen or R1 and R2 together with the nitrogen form a pyrroli- dine ring R3 is hydrogen, methyl or ethyl R4 and R5 are hydrogen ox R4 is methyl or ethyl in the .alpha.-position of the pyrrole ring and R5 in methyl, ethyl or N- propyl in the .alpha.-position of the pyrrole ring X is oxygen, sulfur or Image and Ar in phenyl that may be substituted by chlorine, and their therapeutically useful ammonium salts, alkali metal salts or acid addition salts, which compounds and salts thereof exhibit valuable pharmacological properties, their preperation, therapeutic agents containing these products, and their use as drugs.
332072
Bliesener Jens-Uwe
Geiss Karl-Heinz
Lenke Dieter
Mueller Claus D.
Basf Aktiengesellschaft
Robic Robic & Associes/associates
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