C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/223, 260/267
C07D 295/15 (2006.01) A61K 31/495 (2006.01) C07D 215/08 (2006.01) C07D 295/13 (2006.01)
Patent
CA 1326027
ABSTRACT OF THE DISCLOSURE Compounds of formula (I): A - M - B (I) (in which: M represents a saturated heterocyclic group having from 5 to 7 ring atoms of which 2 are nitrogen atoms, said group being unsubstituted or being substituted at any of its carbon atoms by C1 - C6 alkyl and/or oxo substituents; A represents a halo- substituted benzhydryl substituent; and B represents certain specific substituted alkyl groups) and salts thereof are valuable for the treatment and prophylaxis of disorders arising from circulatory problems, especially those affecting the brain. They may be prepared by reacting a compound of formula A - M - H with a halo or acyloxy derivative corresponding to the alkyl substituent B which it is desired to introduce.
561899
Fujimoto Katsumi
Hirai Koichi
Iwano Yuji
Matsui Yoshiki
Marks & Clerk
Sankyo Company Limited
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