N-benzocycloalkyl-amide derivatives and their use as...

Details N-benzocycloalkyl-amide derivatives and their use as... N-benzocycloalkyl-amide derivatives and their use as...

C - Chemistry, Metallurgy

07

C

C07C 311/20 (2006.01) A61K 31/18 (2006.01) A61K 31/27 (2006.01) A61K 31/38 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) C07C 233/65 (2006.01) C07C 233/80 (2006.01) C07C 235/22 (2006.01) C07C 235/42 (2006.01) C07C 235/56 (2006.01) C07C 237/20 (2006.01) C07C 271/24 (2006.01) C07C 271/56 (2006.01) C07C 275/28 (2006.01) C07C 307/08 (2006.01) C07C 311/07 (2006.01) C07C 311/29 (2006.01) C07C 317/14 (2006.01) C07D 213/82 (2006.01) C07D 261/18 (2006.01) C07D 333/24 (2006.01) C07D 333/34 (2006.01)

Patent

CA 2338198

A compound of formula (I) or a pharmaceutically acceptable salt thereof; or an enantiomer thereof. Compounds of formula (I) are useful as inhibitors or microsomal triglyceride transfer protein (MTP) and apolipoprotein B (ApoB) secretion and accordingly for the prevention and treatment of MTP and Apo B dependent conditions.

L'invention concerne un composé de formule (I), ou un sel pharmaceutiquement acceptable de celui-ci, ou un énantiomère de celui-ci. Les composés de formule (I) sont utilisés pour inhiber la sécrétion de la protéine de transfert des triglycérides microsomique (MTP) et de l'apolipoprotéine B (ApoB), et donc pour prévenir et traiter les états dépendant de MTP et de ApoB.

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