N-biaryl and n-arylheteroaryl piperazine derivatives as...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/06 (2006.01) A61K 31/496 (2006.01) A61P 3/00 (2006.01) C07D 213/38 (2006.01) C07D 295/08 (2006.01) C07D 307/52 (2006.01) C07D 333/20 (2006.01)

Patent

CA 2588595

The present invention relates to certain biarylz and arylheteroaryl piperazine derivatives of Formula (Ia) that are modulators of the 5HT2c receptor. Accordingly, compounds of the present invention are useful for the treatment of 5HT2c receptor associated diseases or disorders, such as, obesity, Alzheimer Disease, erectile dysfunction and related disorders.

L'invention concerne certains dérivés de biaryl et d'arylhétéroaryl piperazine, de formule (Ia) qui sont des modulateurs du récepteur 5HT2C. En conséquence, les composés selon l'invention sont utilisés pour le traitement de maladies ou de troubles associés au récepteur 5HT2C, tels que obésité, maladie d'Alzheimer, dysfonctionnement érectile et troubles apparentés.

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