C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 237/24 (2006.01) A61K 31/24 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01) C07D 213/82 (2006.01) C07D 239/28 (2006.01) C07D 257/04 (2006.01) C07D 261/18 (2006.01) C07D 271/06 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2474373
N-Biphenyl(substituted methyl)aminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
L'invention concerne des dérivés du N-Biphényle aminocycloalkanecarboxamide (à substitution de méthyle). Ces dérivés sont des antagonistes de bradykinine B1 ou des agonistes inverses qui présentent une grande utilisé dans le traitement ou la prévention de symptômes, tels que la douleur et l' inflammation, associés à la voie de la bradykinine B1.
Anthony Neville J.
Bock Mark G.
Feng Dong-Mei
Kuduk Scott D.
Su Dai-Shi
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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