N-heterocyclic alcohol renin inhibitors

Details N-heterocyclic alcohol renin inhibitors N-heterocyclic alcohol renin inhibitors

C - Chemistry, Metallurgy

07

K

260/280, 260/305

C07K 5/06 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) C07D 233/64 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01) C07K 5/08 (2006.01) A61K 37/02 (1990.01) A61K 37/64 (1990.01)

Patent

CA 1310792

ABSTRACT N-Heterocyclic Alcohol Renin Inhibitors Compounds of the formula Image are disclosed wherein R1 is N-heterocyclic moiety. These compounds intervene in the conversion of angiotensin to angiotensin II by inhibiting renin and thus are useful as antihypertensive agents.

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