N-heterocyclyl-substituted amino-thiazole derivatives as...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61P 35/00 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2516234

Aminothiazole compounds with N-containing cycloalkyl at the 2-amino position which are represented by the Formula (I), or a pharmaceutically acceptable prodrug of said compound, or pharmaceutically acceptable salt of said compound, modulate and/or inhibit the cell proliferation and activity of protein kinases.

L'invention concerne des composés d'aminothiazole avec un cycloalkyle contenant N en position 2-amino, lesdits composés étant représentés par la formule (I) ou un promédicament desdits composés acceptable pharmaceutiquement ou un sel desdits composés acceptable pharmaceutiquement. Ces composés permettent de moduler et/ou d'inhiber la prolifération cellulaire ou l'activité des protéines kinases.

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