N-hydroxy-beta-sulfonyl-propionamide derivatives and their...

Details N-hydroxy-beta-sulfonyl-propionamide derivatives and their... N-hydroxy-beta-sulfonyl-propionamide derivatives and their...

C - Chemistry, Metallurgy

07

C

C07C 317/44 (2006.01) A61K 31/16 (2006.01) C07C 317/46 (2006.01)

Patent

CA 2279863

A compound of formula (I) wherein R1, R2, R3, R4 and Q are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use as matrix metalloproteinases inhibitors and for the production of tumor necrosis factor (TNF).

L'invention porte sur un composé de formule (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿ et Q sont définis dans la description, sur des préparations pharmaceutiques le contenant, et sur leur utilisation à des fins médicales comme inhibiteurs des métalloprotéases matrices et générateurs du facteur de nécrose tumorale (TNF).

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