C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/496 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2641579
This invention relates to novel N-hydroxyacrylamide compounds of formula (I) and pharmaceutically acceptable salts thereof . More particularly, it relates to novel N-hydroxyacrylamide compounds and pharmaceutically acceptable salts thereof which act as a HDAC inhibitor, to a pharmaceutical composition comprising the same and to a method of using the same therapeutically in the treatment and/or prevention of HDAC- related disease.
Cette invention concerne de nouveaux composés de N-hydroxyacrylamide de formule (I) et leurs sels pharmaceutiquement acceptables. L'invention concerne plus particulièrement de nouveaux composés de N-hydroxyacrylamide et leurs sels pharmaceutiquement acceptables agissant en tant qu'inhibiteurs de HDAC, une composition pharmaceutique les comprenant et un procédé d'utilisation de ces composés pour le traitement et/ou la prévention de maladies associées à HDAC.
Eikyu Yoshiteru
Itani Hiromichi
Kozuki Yoshihiro
Masunaga Taro
Shirai Fumiyuki
Astellas Pharma Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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