N-hydroxyamide derivatives and use thereof

Details N-hydroxyamide derivatives and use thereof N-hydroxyamide derivatives and use thereof

C - Chemistry, Metallurgy

07

D

C07D 213/74 (2006.01) A61K 31/496 (2006.01) A61P 29/00 (2006.01) C07D 211/46 (2006.01) C07D 211/58 (2006.01) C07D 215/46 (2006.01) C07D 239/42 (2006.01) C07D 241/20 (2006.01) C07D 285/08 (2006.01) C07D 295/18 (2006.01) C07D 401/12 (2006.01) C07D 487/08 (2006.01)

Patent

CA 2570903

The present invention is related to N-hydroxyamide derivatives of Formula (I) and use thereof, in particular for the treatment and/or prophylaxis of autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, cancer, respiratory diseases and fibrosis, including multiple sclerosis, arthritis, emphysema, chronic obstructive pulmonary disease, liver and pulmonary fibrosis.

La présente invention concerne des dérivés N-hydroxyamide représentés par la formule générale (I) et leur application, en particulier dans le traitement et/ou la prévention de maladies auto-immunes, de maladies inflammatoires, de maladies cardiovasculaires, de maladies neurodégénératives, du cancer, de maladies respiratoires et de la fibrose, y compris la sclérose en plaques, l'arthrite, l'emphysème, la maladie pulmonaire obstructive chronique, la fibrose hépatique et la fibrose pulmonaire.

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