N-imidazolyl derivatives of bicyclic compounds and process...

Details N-imidazolyl derivatives of bicyclic compounds and process... N-imidazolyl derivatives of bicyclic compounds and process...

C - Chemistry, Metallurgy

07

D

260/280, 260/305

C07D 233/56 (2006.01) C07D 401/10 (2006.01) C07D 405/00 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1202030

ABSTRACT The present invention relates to new N-imidazolyl derivatives of bicyclic compounds, in particular to N-imidazolyl derivatives of 3,4-dihydro- 2H-1-benzopyran, 2H-1-benzopyran, 1,2,3,4-tetrahydronaphthalene, 1,2-dihydro- naphthalene, indane and indene, to a process for their preparation and to pharmaceutical compositions containing them. The components are strong selective inhibitors of TXA2 synthesis and are stimulators of PG?2 synthesis. Some of the compounds have a strong hypolipaemic activity.

431748

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