N-(iminomethyl)amine derivatives, their preparation, their...

Details N-(iminomethyl)amine derivatives, their preparation, their... N-(iminomethyl)amine derivatives, their preparation, their...

C - Chemistry, Metallurgy

07

D

C07D 333/38 (2006.01) A61K 31/38 (2006.01) C07D 279/20 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2344223

The invention concerns novel N-(iminomethyl)amine derivatives comprising in their skeleton the aminophenylamine, oxodiphenylamine, carbazole, phenazine, phenoxazine or oxodiphenyl motif, their use as medicines and pharmaceutical compositions containing them. The invention concerns in particular the following compounds: -4-{[2-thienyl (imino) methyl]amino}-N- [2-(phenylamino) phenyl]- benzenebutanamide; -4-{[2- thienyl (imino) methyl]amino}- N-[4-(phenylamino) phenyl]- benzenebutanamide; -N'-[4- (10H- phenothiazin - 2-yloxy) phenyl]- 2-thiophenecarboximidamide; -4-(4-{[amino (2-thienyl) methylidene] amino}phenyl) -N-(10H- phenothiazin- 3-ylH) butanamide; -3-[(3-{[amino (2-thienyl) methylidene] amino}-benzyl) amino]-N- (4-anilinophenyl) propanamide; -N'-(4-{2- [(10H-phenothiazin- 3-ylmethyl) amino] ethyl}phenyl- 2-thiophene carboximidamide.

La présente invention a pour objet des nouveaux dérivés de N- (iminométhyl)amines comportant dans leur squelette le motif aminodyphénylamine, oxodiphénalamine, carbazole, phénazine, phénothiazine, phénoxazine ou oxodiphényle, leur utilisation comme médicaments et les compositions pharmaceutiques les contenant. Elle concerne notamment les composés suivants: -4-{[2-thiényl (imino) méthyl]amino}-N- [2-(phénylamino) phényl]- benzènebutanamide; -4-{[2- thiényl (imino) méthyl]amino}- N-[4- (phénylamino) phényl]- benzènebutanamide; -N'-[4- (10H- phénothiazin- 2-yloxy) phényl]- 2-thiophènecarboximidamide; -4-(4-{[amino (2-thiényl) méthylidène] amino}phényl) -N-(10H phénothiazin- 3-yl) butanamide; -3-[(3-{[ amino (2- thiényl) méthylidène] amino}-benzyl) amino]-N- (4-anilinophényl) propanamide; - N'-(4-{2-[ (10H- phénothiazin- 3-ylméthyl) amino] éthyl}phényl (-2- thiophènecarboximidamide.

Affiliated with

Also associated with

Rating

N-(iminomethyl)amine derivatives, their preparation, their... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-(iminomethyl)amine derivatives, their preparation, their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-(iminomethyl)amine derivatives, their preparation, their... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1376341