N-methanesulfonic acid derivatives of...

Details N-methanesulfonic acid derivatives of... N-methanesulfonic acid derivatives of...

C - Chemistry, Metallurgy

07

H

260/230.5

C07H 15/22 (2006.01)

Patent

CA 1077031

N-METHANESULFONIC ACID DERIVATIVES OF 3',4'-DIDEOXYKANAMYCIN B AND THE METHOD FOR PRODUCTION THEREOF ABSTRACT OF THE DISCLOSURE As new semi-synthetic antibiotic derivative are provided N-methanesulfonic acid derivatives of 3',4'- dideoxykanamycin B which are less toxic than the parent antibiotic and have useful high antibacterial activity. They are produced by interacting 3',4'-dideoxykanamycin B, an aldehyde such as paraformaldehyde and sulfurous acid or an alkali metal sulfite reagent. - 1 -

262518

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