N-[n-(3,3-dimethylbutyl)-l-.alpha.-aspartyl]-l-phenylalanine...

Details N-[n-(3,3-dimethylbutyl)-l-.alpha.-aspartyl]-l-phenylalanine... N-[n-(3,3-dimethylbutyl)-l-.alpha.-aspartyl]-l-phenylalanine...

C - Chemistry, Metallurgy

07

K

C07K 5/072 (2006.01) A23L 1/22 (2006.01) A23L 1/236 (2006.01) A23L 2/60 (2006.01) C07K 1/04 (2006.01) C07K 5/06 (2006.01) C07K 17/00 (2006.01) C07K 17/02 (2006.01) C07K 17/10 (2006.01)

Patent

CA 2362878

This invention provides a process for preparing an agglomerate of N-[N-(3,3- dimethylbutyl)-L-.alpha.-aspartyl]-L-phenylalanine 1-methyl ester and a carrier comprising the steps of: (a) providing a premix solution comprising N-[N-(3,3-dimethylbutyl)-L-.alpha.-aspartyl]-L-phenylalanine 1-methyl ester and a binding agent; (b) fluidizing a car- rier; and (c) applying the premix solution of step (a) onto said fluidized carrier to form an agglomerate of said N-[N-(3,3-dimethylbutyl)-L-.alpha.-aspartyl]-L-phenylalanine 1-methyl ester and said carrier. This invention is also directed to the novel agglomerates prepared by the process of this invention.

Cette invention a trait à un procédé de préparation d'un agglomérat de N-[N-(3,3-diméthylbutyl)-L- alpha -aspartyl]-L-phénylalanine 1-méthyl ester et d'un véhicule, lequel procédé consiste, (a), mettre au point une solution premix contenant le N-[N-(3,3-diméthylbutyl)-L- alpha -aspartyl]-L-phénylalanine 1-méthyl ester et un agent de liaison, (b), à fluidifier un véhicule et (c), à appliquer la solution premix formée lors de la phase (a) sur ce véhicule fluidisé de manière à constituer un agglomérat dudit N-[N-(3,3-diméthylbutyl)-L- alpha -aspartyl]-L-phénylalanine 1-méthyl ester et dudit véhicule. L'invention concerne également le nouvel agglomérat préparé grâce à ce procédé.

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