N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid...

Details N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid... N,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid...

A - Human Necessities

61

K

A61K 31/195 (2006.01) A61K 9/08 (2006.01) A61K 31/198 (2006.01) A61K 45/06 (2006.01) C07C 215/50 (2006.01) C07C 227/02 (2006.01) C07C 227/18 (2006.01) C07C 251/24 (2006.01) C07C 229/16 (2006.01)

Patent

CA 2394524

The use of a mono-cationic salt of N,N'-bis(2-hydroxybenzyl)ethylenediamine- N,N'-diacetic acid (HBED) in iron chelating therapy is disclosed. In particular, the invention relates to the intravenous use of a mono-cationic salt of HBED for treating a primate with a condition treatable by an iron chelator such as iron overload, especially transfusional iron overload.

L'invention concerne l'utilisation de sel monocationique d'acide diacétique N,N'-bis(2-hydroxybenzyl)éthylénediamine-N,N'- en traitement par chélation du fer. En particulier, l'invention concerne l'utilisation intraveineuse de ce sel pour le traitement d'un primate dont l'état justifie le traitement par chélation du fer du type surcharge en fer, notamment la surcharge en fer par transfusion.

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