N,n-bridged, nitrogen-substituted carbacyclic...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/16 (2006.01) A61K 31/407 (2006.01) C07D 209/00 (2006.01) C07D 243/00 (2006.01) C07D 487/22 (2006.01)

Patent

CA 2502200

The present invention relates to novel protein kinase inhibitors with advantageous pharmaceutical properties, methods for their preparation, intermediates thereof and pharmaceutical compositions comprising the same, reagents containing the same, and methods of using the same as therapeutics, particularly in CNS diseases.

L'invention concerne des inhibiteurs de protéine kinase à propriétés pharmaceutiques avantageuses, des procédés d'élaboration correspondants, des intermédiaires correspondants, et des compositions pharmaceutiques renfermant ces inhibiteurs, des réactifs qui les contiennent, et des procédés relatifs à l'utilisation des inhibiteurs en question comme agents thérapeutiques, en particulier pour le traitement des maladies du système nerveux central.

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